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CSI solvers have been tried and tested by the industry for over 45 years. The SAPFire Analysis Engine can support multiple 64-bit solvers for analysis optimization and can perform both eigen analysis and Ritz analysis. Parallelization options are available to take advantage of multiple processors.
Each of these programs offers unique capabilities and tools that are tailored to different types of structures and problems, allowing users to find just the right solution for their work. SAP2000 is intended for use on civil structures such as dams, communication towers, stadiums, industrial plants and buildings. CSiBridge offers powerful parametric design of concrete and steel bridges. ETABS has been developed specifically for multi-story commercial and residential building structures, such as office towers, apartments and hospitals. The SAFE System provides an efficient and powerful program for the analysis and design of concrete slabs and foundations, with or without post-tensioning. PERFORM-3D is a highly focused nonlinear tool offering powerful performance based design capabilities.
\\r\\n\\t\\t\\tThird-party developers, such as CAD and 3D modeling developers, can use the API to enable their software with all of the sophisticated analysis and design technology of CSI software. Developers can create rich and tight two-way links with CSI software, allowing for accurate transfer of models, complete control of execution, and extraction of analysis and design information, all from within their application. \\r\\n\\t\\t\\t
Computers and Structures, Inc. (CSI) is seeking an experienced developer to join our\\r\\n development team in Walnut Creek, California where they will be tasked with improving the\\r\\n graphical display in our line of engineering analysis software, using DirectX or OpenGL. The\\r\\n chosen candidate shall be highly motivated and have a passion for computer graphics. This\\r\\n position will include development of new features, as well as improving the existing graphical\\r\\n display to make the end user experience more enjoyable and easy to use.
A Ph.D. or extensive\\r\\n experience in the field of structural engineering and/or structural mechanics, with a strong\\r\\n background in one or more of the following areas: structural dynamics, mechanics of\\r\\n materials, nonlinear material behavior, computational mechanics, finite element analysis,\\r\\n and numerical analysis of large linear and nonlinear systems.
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The Software that you are about to access is a structural design and analysis tool developed by Computers & Structures, Inc., a California corporation (\\\"Vendor\\\"). This End-User Software License Agreement (this \\\"Agreement\\\") sets forth the terms under which you, as an individual or entity authorized by Vendor (or, for entities, any employee or agent you authorize to use the Software) (\\\"you\\\"), may use the Software.
EPA's Storm Water Management Model (SWMM) is used throughout the world for planning, analysis, and design related to stormwater runoff, combined and sanitary sewers, and other drainage systems. It can be used to evaluate gray infrastructure stormwater control strategies, such as pipes and storm drains, and is a useful tool for creating cost-effective green/gray hybrid stormwater control solutions. SWMM was developed to help support local, state, and national stormwater management objectives to reduce runoff through infiltration and retention, and help to reduce discharges that cause impairment of waterbodies.
Preparation and chromatographic analysis of FITC- chitosan oligosaccharides a The standard curve of FITC solution; b Typical standard calibration curve for the determination of FITC-COS in the ovary. c HPLC chromatograms of FITC; d HPLC chromatograms of FITC-COS
Conceptualization and methodology, Yaoqi Huang and Yuehui Zheng; validation and formal analysis, Yaoqi Huang, Haifeng ye and Chuan Hu; writing and revising, Yaoqi Huang, Feiyin Zhu and Yuehui Zheng; funding acquisition, Yuehui Zheng. The author(s) read and approved the final manuscript..
Computer animation was gradually developed since the 1940s. 3D wireframe animation started popping up in the mainstream in the 1970s, with an early (short) appearance in the sci-fi thriller Futureworld (1976).[citation needed]
Traditional animation (also called cel animation or hand-drawn animation) was the process used for most animated films of the 20th century.[38] The individual frames of a traditionally animated film are photographs of drawings, first drawn on paper.[39] To create the illusion of movement, each drawing differs slightly from the one before it. The animators' drawings are traced or photocopied onto transparent acetate sheets called cels,[40] which are filled in with paints in assigned colors or tones on the side opposite the line drawings.[41] The completed character cels are photographed one-by-one against a painted background by a rostrum camera onto motion picture film.[42]
Rotoscoping is a technique patented by Max Fleischer in 1917 where animators trace live-action movement, frame by frame.[57] The source film can be directly copied from actors' outlines into animated drawings,[58] as in The Lord of the Rings (US, 1978), or used in a stylized and expressive manner, as in Waking Life (US, 2001) and A Scanner Darkly (US, 2006). Some other examples are Fire and Ice (US, 1983), Heavy Metal (1981), and Aku no Hana (Japan, 2013).[citation needed]
Stop-motion animation is used to describe animation created by physically manipulating real-world objects and photographing them one frame of film at a time to create the illusion of movement.[61] There are many different types of stop-motion animation, usually named after the medium used to create the animation.[62] Computer software is widely available to create this type of animation; traditional stop-motion animation is usually less expensive but more time-consuming to produce than current computer animation.[62]
3D animation is digitally modeled and manipulated by an animator. The 3D model maker usually starts by creating a 3D polygon mesh for the animator to manipulate.[94] A mesh typically includes many vertices that are connected by edges and faces, which give the visual appearance of form to a 3D object or 3D environment.[94] Sometimes, the mesh is given an internal digital skeletal structure called an armature that can be used to control the mesh by weighting the vertices.[95][96] This process is called rigging and can be used in conjunction with key frames to create movement.[97]
A full flight over an orchard at 120 m ( 400 ft) with images captured with 75% overlap using the MicaSense Altum sensor. It includes captures of a calibrated reflectance panel. The original TIF outputs were stacked into a single TIF per frame using the MicaSense imageprocessing library with slight modifications by DroneMapper. The original imageprocessing library is located here. The forked library to produce DroneMapper TIF input is located here.
Four values (K22, K23, K32, and K33) of a typical 6x6 matrix for foundation stiffness may be generated by the program for a range of loading or deformation. These values can be used to model nonlinear foundation springs in the analysis of the superstructure.
To study the effect of translation disorder mediated by abnormal m7G modification, we performed polyribosome-bound mRNAs sequencing (polyribosome-seq) (Fig. 3m) using the METTL1 knockdown and control ESCC cells. To investigate the link between the mRNA translation and tRNA m7G modification, we calculated the number of the codons decoded by the m7G-modified tRNAs on differentially translated mRNAs. Our data revealed that the mRNAs with reduced translation efficiencies (TEs) have notably larger number of codons decoded by m7G-modified tRNAs (Fig. 3n). Gene ontology analysis and pathway analysis showed that TE-down mRNAs are significantly enriched in autophagic biological process and mTOR signaling pathway (Fig. 3o, p and Supplementary Table 1). Notably, those mRNAs with decreased TEs and involved in autophagic biological process or mTOR signaling pathway have larger number of codons decoded by m7G-modified tRNAs than other detected mRNAs (Fig. 3q). Furthermore, our ribosome profiling sequencing (Ribo-seq) data showed that mRNAs with decreased translation efficiencies have larger number of m7G-tRNA-dependent codons (Supplementary Fig. 4g, h), and METTL1 knockdown promoted ribosome pausing at codons decoded by m7G tRNAs (Supplementary Fig. 4i), suggesting that METTL1-mediated m7G tRNA modification is essential for ribosome transition on m7G codons. Gene set enrichment analysis (GSEA) of the differentially translated mRNAs identified by Ribo-seq also revealed that METTL1 regulates the translation of transcripts related to negative regulation of autophagy and mTOR signaling pathway (Supplementary Fig. 4j).
ESCC tumor and adjacent normal esophageal tissues from 120 esophageal carcinoma patients who underwent esophagectomy between September 2002 and July 2019 were obtained from the Sun Yat-Sen University Cancer Center (Guangzhou, China). Baseline information of patients was shown in Supplementary Table 2. Paraffin-embedded specimens were used for immunohistochemistry (IHC) analysis. Informed consents were obtained from all patients prior to analysis. All patient-related studies were reviewed and approved by the Institutional Review Board of the hospital (B2021-131-01). The datasets from The Cancer Genome Atlas (TCGA) and cBioPortal for Cancer Genomics were used for analysis of the expression and clinical association between METTL1/WDR4 and ESCC prognosis. 153554b96e
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